Nadim · Golowasch · Bucher

Welcome to the STG lab!

Our laboratory is part of the Federated Department of Biological Sciences of the New Jersey Institute of Technology (NJIT) and Rutgers University Newark. It is run by three Principal Investigators, Farzan Nadim, Jorge Golowasch, and Dirk Bucher, all faculty in the department. We use both experimental and theoretical approaches to study the neurophysiology of a small central pattern generating circuit in lobsters and crabs, the stomatogastric ganglion (STG). Central pattern generators (CPGs) are networks of nerve cells in the central nervous system that generate the basic patterned electrical activity underlying most rhythmic behaviors like walking and breathing in all animals. We are taking advantage of the experimental accessibility of the crustacean nervous system to uncover fundamental principles that govern neural processing across all animal and human nervous systems.

  • STG neurons3D reconstructions of confocal images
  • Central Pattern GenerationThe pyloric circuit and the rhythm it produces
  • Decapod CrustaceansJonah crab and Maine lobster, our experimental animals
  • Neuropil structure of the STGCrab (l, m) and lobster (r) STGs. Stained synaptic contacts are shown in red.
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News

Postdoc position open immediately!

A postdoc position is available immediately, for a collaboration with Dr. Horacio Rotstein from the NJIT Math Department. Solid expertise in electrophysiology (voltage-clamp minimum) and a sufficient background in computational neuroscience to comfortably interact with modelers and mathematicians is required. Work will consist of measuring and manipulating (with dynamic clamp) voltage-gated currents in individual or multiple cells simultaneously in order to understand the role of ion current co-expression in STG neurons.

If you are interested, send your CV and names of potential references as soon as possible to Jorge Golowasch, golowasch@njit.edu, ☎ 973-353-1267.

New Lab Members

Herve Nganguia, Ph.D. joined the lab as a postdoctoral fellow. Herve received his Ph.D. in Mathematics at NJIT for work on fluid dynamics. He is interested in computational neuroscience and will be working on the theoretical implications of axonal neuromodulation for neural coding.

Xinping (Lily) Li joined the lab as a graduate student. Lily received her undergraduate degree from Hongkong Baptist University and joined the Biology Ph.D. Program in 2013. She is interested in both experimental and theoretical neurophysiology and will study neuropeptide modulation of circuit dynamics.

Latest Papers

Hua-an Tseng, Diana Martinez, and Farzan Nadim published a paper on the implications of resonance properties for network function in The Journal of Neuroscience:

Tseng HA, Martinez D, Nadim F (2014) The frequency preference of neurons and synapses in a recurrent oscillatory network. J Neurosci 34:12933-45.   PubMed  

Farzan Nadim and Dirk Bucher published a review on neuromodulation for an upcoming special issue in Current Opinion in Neurobiology:

Nadim F, Bucher D (2014) Neuromodulation of neurons and synapses. Curr Opin Neurobiol 29C:48-56.   PubMed  

Jorge Golowasch published a review on the regulation of neuronal excitability:

Golowasch J (2014) Ionic Current Variability and Functional Stability in the Nervous System. BioScience 64:570-580.   Journal