Nadim · Golowasch · Bucher

Welcome to the STG lab!

Our laboratory is part of the Federated Department of Biological Sciences of the New Jersey Institute of Technology (NJIT) and Rutgers University Newark. It is run by three Principal Investigators, Farzan Nadim, Jorge Golowasch, and Dirk Bucher, all faculty in the department. We use both experimental and theoretical approaches to study the neurophysiology of a small central pattern generating circuit in lobsters and crabs, the stomatogastric ganglion (STG). Central pattern generators (CPGs) are networks of nerve cells in the central nervous system that generate the basic patterned electrical activity underlying most rhythmic behaviors like walking and breathing in all animals. We are taking advantage of the experimental accessibility of the crustacean nervous system to uncover fundamental principles that govern neural processing across all animal and human nervous systems.

  • STG neurons3D reconstructions of confocal images
  • Central Pattern GenerationThe pyloric circuit and the rhythm it produces
  • Decapod CrustaceansJonah crab and Maine lobster, our experimental animals
  • Neuropil structure of the STGCrab (l, m) and lobster (r) STGs. Stained synaptic contacts are shown in red.
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The Lab moved to the NJIT campus!

We left Boyden Hall on the Rutgers campus and moved across the street to the newly renovated 4th floor of the Central King Building on the NJIT campus, with more space and completly new furnishings!

Lab Members

Diana Martinez, Ph.D. successfully defended her PhD thesis and moved to McGill University to join Maurice Chacron's lab, where she will work on neural coding in electric fish. Congratulations!

Veronica Garcia, Ph.D. successfully defended her PhD thesis and moved to L.A. to join Clive Svendsen's lab at Cedars-Sinai Medical Center to work on ALS and Parkinson's disease. Congratulations!

Michael Gray, Ph.D. successfully defended his PhD thesis and will stay on in the lab as a postdoctoral researcher for a while. Congratulations!

Elizabeth Cronin, M.S., former Master's student in our program, and Laboratory Technician in our lab, joined our PhD program to do her thesis research in the lab. Congratulations!

Latest Papers

Farzan Nadim published a theory paper on network modulation in the Journal of Computational Neuroscience, with collaborators Nick Kintos (Saint Peter's) and Mike Nusbaum (UPenn):

Kintos N, Nusbaum MP, and Nadim F (2016) Convergent neuromodulation onto a network neuron can have divergent effects at the network level. J Comput Neurosci 40(2):113-135.   PubMed  

Dirk Bucher published a chapter on axon physiology in a book edited by Kathleen Rockland:

Bucher D (2015) Contribution of axons to short-term dynamics of neuronal communication. In: Axons and Brain Architecture (Rockland KS, ed). Elsevier, Boston  Google books  

Veronica Garcia, Nelly Daur, and Dirk Bucher, together with the Schulz lab at Mizzou, published a paper on cell-type specific neuropeptide receptor expression in The Journal of Neuroscience:

Garcia VJ, Daur N, Temporal S, Schulz DJ, and Bucher D (2015) Neuropeptide receptor transcript expression levels and magnitude of ionic current responses show cell type-specific differences in a small motor circuit. J Neurosci 35:6786-6800.   PubMed